Giants vs. Mariners Prediction, Odds, Picks - April 5

Data Skrive

Willy Adames and the San Francisco Giants will play Julio Rodriguez and the Seattle Mariners on Saturday at Oracle Park, at 9:05 p.m. ET. The favored Giants have -125 moneyline odds against the underdog Mariners, who are listed at +106. San Francisco is the favorite on the run line (-1.5). The contest’s over/under has been set at 7 runs.

Take a look at everything you need to know from a betting perspective on the Giants-Mariners game, regarding the run line, moneyline and total, plus expert picks.

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Giants vs. Mariners Game Information & Odds

When: Saturday, April 5, 2025 at 9:05 p.m. ET
Where: Oracle Park in San Francisco, California
How to watch on TV: NBCS-BA and ROOT Sports NW

Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Giants -125 +106 7 -119 -101 -1.5 +173 -208

Giants vs. Mariners Prediction

Score Prediction: Giants 4, Mariners 3
Total Prediction: Under 7 runs
Win Probabilities: Giants 52%, Mariners 48%

Giants vs. Mariners Betting Insights

The Giants have won both games they’ve played as favorites this season.
San Francisco has played as favorites of -125 or more once this season and won that game.
The Giants have a 55.6% chance to win this game based on the implied probability of the moneyline.
The Mariners came away victorious in the one game they played as the underdog this season.
Oddsmakers have given Seattle the worst odds of winning it has seen this season with a +106 moneyline listed for this contest.
The moneyline set for this matchup implies the Mariners have a 48.5% chance of coming away with a victory in the contest.

Giants Player Insights

Wilmer Flores leads the Giants with four home runs and 10 runs batted in.
Flores is third in home runs and eighth in RBI among all batters in baseball.
Heliot Ramos is hitting .269 with three doubles and three home runs.
Ramos is 11th in home runs and 18th in RBI among all hitters in baseball.
Ramos has six straight games with at least one hit. In his last six games he is batting .269 with three doubles, three home runs and seven RBI.
Jung Hoo Lee leads the Giants with a .278 batting average.
Lee is on a four-game hitting streak entering this contest. In his last five games he is batting .278 with three doubles, three walks and two RBI.
Matt Chapman has a home run and four walks while hitting .238.

Mariners Player Insights

Randy Arozarena has put up a team-high two home runs.
Among all batters in MLB, Arozarena’s home run total is 24th and his RBI tally ranks 133rd.
Rodriguez has a triple, a home run and five walks while hitting .182.
Rodriguez is 58th overall in homers and 84th in RBI this season.
Jorge Polanco has a team-high four runs batted in.
Dylan Moore has a home run and three walks while hitting .375.