Data Skrive

Steven Kwan and the Cleveland Guardians play the Los Angeles Angels on Sunday at Angel Stadium. Ian Anderson will be on the mound for Los Angeles, with first pitch at 4:07 p.m. ET. Oddsmakers list the Guardians as -152 moneyline favorites, while giving the underdog Angels +127 moneyline odds. Cleveland (-1.5) is favored on the run line. The over/under for the contest is set at 8.5 runs.

Here’s everything you need to know from a betting perspective on the Guardians-Angels game, regarding the run line, moneyline and total, plus expert picks.

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Check out the top moments between the Seattle Mariners and the Los Angeles Angels.

Guardians vs. Angels Game Information & Odds

• When: Sunday, April 6, 2025 at 4:07 p.m. ET
• Where: Angel Stadium in Anaheim, California
• How to watch on TV: FDSW and CLEG

Favorite Favorite Moneyline Underdog Moneyline Total Over Total Odds Under Total Odds Run Line Favorite Run Line Odds Underdog Run Line Odds Guardians -152 +127 8.5 -123 +102 -1.5 +114 -136

Guardians vs. Angels Prediction

• Score Prediction: Guardians 5, Angels 4
• Total Prediction: Over 8.5 runs
• Win Probabilities: Guardians 56%, Angels 44%

Guardians vs. Angels Betting Insights

• The Guardians won the only game they’ve played as the favorite this season.
• Cleveland has not entered a game this season as bigger favorites on the moneyline than the -152 odds on them winning this game.
• Oddsmakers have implied with the moneyline set for this matchup that the Guardians have a 60.3% chance to win.
• The Angels have won in two of the four contests they have been named as odds-on underdogs this year.
• Los Angeles has played as an underdog of +127 or more just one time this year and came away with a win in that game.
• The moneyline set for this matchup implies the Angels have a 44.1% chance of walking away with the win.

Guardians Player Insights

• Jose Ramirez supplies the Guardians with an injection of both power and average, leading the team in dingers with four and hitting at .381. He has also knocked in six runs this season.
• Of all hitters in MLB, Ramirez ranks fourth in homers and 35th in RBI.
• Ramirez takes a hitting streak of two games into this game. During his last five outings he is batting .471 with two doubles, four home runs, two walks and five RBI.
• Kyle Manzardo’s eight runs batted in pace his team.
• Manzardo is 36th in home runs and 14th in RBI in the major leagues.
• Kwan has a double, a home run and three walks while hitting .333.
• Kwan is on a three-game hitting streak entering this contest. During his last five outings he is hitting .300 with two walks and an RBI.
• Gabriel Arias is batting .333 with a double, a home run and two walks.
• Arias has recorded at least one hit in five games in a row. During his last five outings he is hitting .375 with a home run, two walks and two RBI.

Angels Player Insights

• Kyren Paris is hitting .545 with a triple, a home run and two walks.
• Among all hitters in the majors, Paris’ home run total is 74th and his RBI tally ranks 116th.
• Paris has collected a hit in five straight games. During his last five outings he is hitting .600 with a triple, a home run, two walks and three RBI.
• Mike Trout has driven in the most runs for the Angels with six runs batted in.
• Trout is currently 36th in home runs and 35th in RBI in the major leagues.
• Logan O’Hoppe has been solid source of run production for the Angels with three long balls and six runs batted in.
• Nolan Schanuel leads the Angels with a team-leading batting average of .286.

Check out the top moments between the Seattle Mariners and the Los Angeles Angels.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Los Angeles Angels

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