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The 2025 NASCAR Cup Series season resumes on Sunday, when Denny Hamlin and Kyle Larson will try to build off their successful four-week runs before the break at the 2025 Jack Link’s 500. Hamlin and Larson have won two of the last four NASCAR Cup Series races, with Larson most recently winning the Food City 500 on April 13. The season resumes at one of the most iconic locations in racing, Talladega Superspeedway, so how should a trip to Talladega affect how you form a Jack Link’s 500 NASCAR DFS strategy?

Brad Keselowski is the winningest driver in the Jack Link’s 500 NASCAR DFS driver pool at Talladega Superspeedway with six victories. He has at least double as many wins as every other driver available for NASCAR at Talladega DFS lineups, but he’s only won one race overall since the beginning of the 2022 NASCAR Cup Series season. How should you balance the past and present for Keselowski for Jack Link’s 500 NASCAR DFS lineups? Before locking in any NASCAR DFS picks for the Jack Link’s 2025 on sites like DraftKings and FanDuel, be sure to check out the optimal NASCAR at Talladega DFS strategy and advice from SportsLine’s Mike McClure. 

McClure has won over $2 million in his career as a daily Fantasy pro, and his NASCAR DFS driver pool, projections and advice can help you score a big win on Sunday on sites like FanDuel and DraftKings.

McClure’s model began its 2025 season by calling Chase Elliott to win for a +300 payout at the Clash at Bowman Gray and was also high on Byron as a +2000 longshot at Daytona. Then last week, it predicted Kyle Larson’s win in Miami for a +350 payout. In 2024, it nailed Larson to win in Las Vegas for a 21-5 sports betting payout and predicted Denny Hamlin’s wins in Bristol at 5-1 and Richmond at 17-4.

It also impressively nailed five of Larson’s wins during his historic season in 2021. All told, the model has nailed a whopping 20 winners since 2021, including nine in 2023 and three in the first seven races last season. Anyone who followed its lead on betting apps and sportsbooks on those NASCAR picks could have seen huge returns.

Now, he’s turned his attention to Sunday’s Jack Link’s 500. He’s only sharing his picks and NASCAR DFS driver pool here.

Top 2025 Jack Link’s 500 NASCAR DFS picks

For NASCAR at Talladega, McClure is high on Kyle Busch ($8,800 on DraftKings and $12,000 on FanDuel). The 63-time NASCAR Cup Series winner takes the wheel for the final time as a man in his 30s at a legendary speedway he’s conquered both earlier and later in his career. Busch, who turns 40 on May 2, won races 15 years apart at Talladega Speedway with a victory in 2008 and 2023. He won the GEICO 500 in April 2023 at Talladega Speedway, and he’s led multiple laps in each of his last eight NASCAR at Talladega events. 

Busch finished in the top five in a stage in each of his last two Talladega Speedway races. Busch started this season with three top-10 results over his first four races. After a week off, McClure expects the rest to bode him well as Busch makes his 40th career start at Talladega Speedway, ironically just as he’s about to reach that age as well.

Part of McClure’s optimal NASCAR DFS strategy also includes rostering Tyler Reddick ($8,400 on DraftKings and $8,200 on FanDuel). Reddick has finished in the top 10 in two of his last four races and has three top-five results this year, which is tied for the fifth-most in NASCAR. The 27-year-old is seventh in the NASCAR Cup Series standings after finishing a career-high fourth with a career-best 12 top-five results and 21 top-10 finishes last year.

Reddick took advantage of a crash on the final lap to sneak through an opening and win last year’s spring race at Talladega Speedway, taking the GEICO 500. It was one of his three victories last season, which tied a career-high, and he’s had at least one top-10 finish in a stage in each of his last three NASCAR at Talladega events. Reddick has also led multiple laps in three straight NASCAR at Talladega events and given his price, McClure sees value in adding Reddick to Jack Link’s 500 NASCAR DFS picks. See which other drivers to roster here.

How to set 2025 NASCAR at Talladega DFS lineups

McClure is also targeting an undervalued driver set to return plenty of value for his NASCAR DFS picks. He’s in a prime position to make a run at the checkered flag and comes at a price that won’t break the bank. You can see who it is, and every other pick, right here.

So what are the top NASCAR DFS picks for NASCAR at Talladega 2025? And which value driver is a must-roster? Visit SportsLine now to see DFS millionaire Mike McClure’s complete driver pool for DraftKings and FanDuel, for a chance to cash in big on NASCAR DFS.