Milwaukee Brewers vs Pittsburgh Pirates Predictions, Parlay, Picks, Odds — 5/22

The Pittsburgh Pirates host the Milwaukee Brewers on May 22, 2025. First pitch from PNC Park is scheduled for 6:40 p.m. ET; the game will be broadcast on SportsNet PT.

Find my MLB betting preview and Brewers vs Pirates prediction below, as well as probable pitchers, betting trends, injury reports and more.

Place This Parlay Instantly!

My Brewers vs Pirates Predictions, Parlay

  • Pirates ML
  • Rhys Hoskins 1+ Hit

Parlay Odds: +250 (BetMGM)

Brewers vs Pirates Odds

Thursday, May 22

6:40 p.m. ET

SportsNet PT

Brewers OddsSpreadTotalMoneyline-1.5

+135

9

-110o / -110u

-125

Pirates OddsSpreadTotalMoneyline+1.5

-160

9

-110o / -110u

+105

Brewers vs Pirates Preview, Parlay Picks

This is the first of a four-game series between Pittsburgh and Milwaukee.

The Pirates are 17-33 this year but 11-14 at PNC Park, while the Brewers are 24-26 this year but just 9-16 on the road.

Mike Burrows takes the mound for the Pirates on Thursday in his first career start.

The Pirates have won two straight and their bats will lead Burrows to victory in this one. Take the Pirates moneyline.

Rhys Hoskins has been raking off right-handed pitchers this year, with a .311 average and .915 OPS.

Hoskins has been on fire in the past week, hitting .350, which is well above his standard.

The Brewers’ first baseman will have a big game versus Burrows in his first career start.

Brewers vs Pirates Parlay

  • Pirates ML
  • Rhys Hoskins 1+ Hit

Parlay Odds: +250 (BetMGM)

Brewers vs Pirates Betting Trends

Brewers vs Pirates Weather

Get the latest coverage on MLB Weather.

Premium picks, tools & analysis

Track & follow smart money

Biggest player prop edges

Real-time expert pick alerts

Leave a Reply

Your email address will not be published. Required fields are marked *